Programs like BitComet and utorrent work right out of the box (once you have told your firewall to let them through), if there's not anything peculiar going on with your connection, like a requirement for port forwarding. However, it's still worth it to browse through all the settings, even if you didn't understand all of them right away - I certainly didn't when I first time launched BitComet a somewhat long time ago. The same thing with utorrent later. Still, there are some obvious things worth tweaking, and then things explained clearly in the help files that can enhance the program's performance considerably.

It's a program you'll be running for countless hours depending only on how much anime you want to watch, so it only makes sense to try to make it run as smoothly as possible within reasonable limits. It's not like I studied for days how to alter the utorrent settings. More like one hour summed up, perhaps, over time, and it was absolutely worth it.