Quote Originally Posted by MFauli View Post
Im looking for anime with teenage boys/young men as lead characters, that are socially incompetent and feel left out, but then suddenly somehow get into bigger happenings. Examples from the top of my head would be Chaos Head or Welcome to the NHK. Anything else like that?
Now and Then, Here and There

Sora no Otoshimono (there is lots of humor, but the undertones are pretty serious, especially when you get into the upcoming second season)

Eureka 7

Peacemaker Kurogane

Le Chevalier D'Eon

Black Lagoon

Busou Renkin

Elfen Lied

Kono Minikuku mo Utsukushii Sekai

Last Exile

Outlaw Star

Neon Genesis Evangelion


Saber Marionette J (humor at the beginning, none toward the end)

Solty Rei (old guy)

Summer Wars (movie)

Venus Wars (movie)

These will probably fit the bill. The concept you want has more prevalence in manga I think.

Series I am less sure about (because I haven't seen them):

Fantastic Children