Lol, there are no characters who are universally appealing.

Anyway we need more scenarios. How might Tsunade die? When she finds out about Jiraiya will she just rush off to the rain village? I can see a fight between her and Pein going very differently than Pein vs Jiraiya due to her super strength (just imagine her beating up giant summons) but in the end the multiple bodies and immortality would most likely lead to her down fall. But maybe she'll discover the secret of the shared vision thing and develop a counter of some sort first.

Or...will Jiraiya's death give Danzou more clout as a proponent of taking a more harsh stance towards things in order to ensure security? I'm not sure how this would work, but somehow that could lead to Tsunade being ousted and then assassinated thanks to a nefarious trap!