So if you don't die from GN-particles infection, you become an innovator. That makes sense, considering Setsuna and Louise are the only two human-turned-innovator beings. One's alive on medication while the other' cured by quantum particle emission.

Regarding Lyle's face as he muttered Niel's name....I was thinking something different. He was pointing his gun at Setsuna, just as Niel did on the island after learning he was from the KPSA. More likely, he's now truly understanding how his brother felt. The rage...but also the ability to forgive (or at least not shoot) Setsuna. Before, when they told him about that, he said that he could think straight, that he is out there to change the world, so as not to be swayed by vengence like his brother was.

Today, however, he says that he's fighting not for Kataron nor CB, but for himself. Besides his less impressive skill, Lyle is pretty much Lockon.

It bugs me too how Regene can run aloof without Ribbons killer her around each corner, but really want to see her knock him off his arrogant ass just as he did to Alexanjro, so that's alright.