I'm glad Mikoto brought up that using her powers uses up energy though. I don't think it was ever really mentioned that using their powers actually costs them anything. I'm honestly not sure how much I can count on this being fact, or just being an inconsistent, one-off comment. If this is true, that means Accelerator can be overwhelmed if we forced him to use his Reflect enough times.
One nuke wouldn't work, but how about 3?