She didn't think that Takitsubo was a small fry. She felt something dangerous from her, so she ran, which is the best tactical decision at that time because trying to attack 2 espers with unknown powers (one of which erased huge metal objects and shot beams) and another esper that had bombs all over the place alone is just stupid.

After she ran, she had her hands full just not getting melted. I don't really see how she can take care of the other two first, especially because Mugino will protect them, as she said so herself in this episode, even if it is just for the sake of keeping her tools safe.