i thought of something even better: Naruto and his friends manage to find a way to negate the Sharinganīs power forever. Like, making mankind immune to its effects. Robbing Sasuke of his fancy Uchiha-powers. Without them, heīs just a better-than-average fighter, but no monstrous threat to a whole ninja nation. And since heīs so proud of his bloodline, itīd hit him the hardest.
As an alternative, have him somehow lose to Sakura in a real fight. Then after heīs beaten, Sakura gives Naruto a juicy kiss and the engage each other. While Sasuke is watching that scene, Orochimaru starts raping him.