It's an exceptionally well-done Imperial Court era series. Charismatic as hell main and supporting cast. There is a mix of medical mysteries, political scheming, a few conspiracies, and sex education. It's well-composed and very well animated. No magic, no isekai, intelligent characters who don't act stupidly for plot sake (aside from the lead drinking poison for fun/science), and its not an ecchi series.
And if you want to listen to Yuuki Aoi as the lead make a full menagerie of amusing weird noises, this anime is #1 on that list.
It was scheduled to start a few weeks late last season so it is a bit of a sleeper hit.