His disease appears to be his onl handicap. He really doesn't look afraid of Naruto at all right now. Heck he didn't even go Level 1 or Level 2, he just took out some blades and coiled up into position.

Whatever happens, this fight won't be over quick. I kind of look for Naruto to win this fight because Kabuto seems to think that Kimimaro and Sasuke are near the same level.