I would be very pleased to have Itachi show up. I'd like to see some other villain other than Oro get some face time. I just don't agree with a welp like Sasuke being the one to kill Itachi.
Well, I did say kill didn't I. So I guess there could be people to beat Itachi, but Sasuke will most likely be the one to beat and kill Itachi. When you really think about it. None of the genins have ever killed anyone. I don't think that Sasuke will kill Itachi in the end. I think that he'll let Itachi live, a broken man; something like that. I just can't see Sasuke surpassing his brother.
The introduction of Itachi will also mark the official introduction of Akatsuki. I would like to know more about this organization. I hope that it'll mark the closing of the manga. I feel that there is more quality to a manga when the stories aren't dragged on for too long. If it gets dragged on then we get a lot of filler and not much qaulity.