Sakura's only benefit is expert chakra control and her smartness. She'll probably be a medic ninja.
But how many doctors do you know are 12 years old? The only reason i'll see her learn under Tsunade is because Tsunade was a ninja medic. Thats why I would believe Tsunade would someday teach Sakura.

As she is now, she a definite liability.

For Sasuke. Nothing much can be said about him. He's totally obsessed to be stronger just for revenge. His a liability from the start. A brilliant character but too mentally unstable to be of any proper use.