Ive got a bit of a new theory, although it doesnt have much to back it up. On page 8, there is the low evil laugh (Fu Fu Fu). Isnt that Oro's laugh? We cant see who Mr. Uchiha is talking to, nor can we see his silouette (sp?). Im thinking maybe this is Oro, before leaving the leaf. Again, this is a very weak theory, but Im thinking maybe Itachi knew Oro was going after the Uchiha ability, and rather then see it in the hands (or eyes i guess) of Oro, he decided to slaughter his family. Seems like a rather extreme way around things, but hey... weak theory.

Regardless of how dumb you guys may think this whole thing is, Im pretty certain that the laugh was Oro's.