actually, all sakura hating aside...
the story and feel of the show would change quite a bit of they had sakura eventually take down kabuto. i'd like to see it happen and i think it would give more weight to her character and her abilities and further the show's theme of the various genin's growth and development along well.
i wonder if she'd get super strong, too? though i thought that was a tsunade side-effect cause of her blood.. perhaps she'll get something else...